Basic Information
VIS ID
TVIS42000190
Fusion event
EBV-LARGE1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
1447
Orient
-
Integrated sequence
GGCAGTGGAAATAGAACATACGGTCCAGTTTTTATGTGCCTCGGTGGCCTGCTCACCATGGTAGCCGGCGCTGTGTGGCTGACGGTGATGTCTAACACGC| |TTTTGTCTGCCTGGATTCTTACAGCAGGATTCCTGATTTTCCTCATTGGTAAGTGTGACACCAACAGGTGTTGCCTTGTTATGTCACCGTTCTGACACAT
Host Sequence
Chromosome
chr22
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
34311014/33915026 (Hg38)
End
34311014/33915026 (Hg38)
Orient
+
Location type
Intronic
Target gene
LARGE1
miRNAs that regulate target gene
hsa-mir-18a-5p
Nearest miRNA
hsa-mir-1286/Upstream/478357; hsa-let-7a-3/Downstream/1420614;
Nearest TSS
ENST00000624155/Upstream/25798; ENST00000610170/Downstream/5388;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/264415, chr22-CpG: 275/Downstream/4827
Upstream sequence
tgatcccctgGGGCTTGATTAAAGCATCCTGTCTCCCAATCAACATAGGGATGGATGATAGAGACAAGacaaacatacaaacacaaacacacacacacac
Downstream sequence
acacacacacacacacagagagagagagagagagagagGCTTCTAACTTTTATTCCCATTATCCTTCTGGCTGCTGTTTCTAAAAACTATACTAAATATA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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