Basic Information
VIS ID
TVIS42000192
Fusion event
EBV-EP300-AS1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
46568
Orient
+
Integrated sequence
GGCGTTTAAAGAAGAGAATAGTGGCCAGGGCCTCGGTGGGGTCCAGCGTGAGGTCTTATTTTTGAAAAGGGATATTATAAAACAGGTCATTGCTCGGATT| |GTGGCAGCCGATAGCACCCTAGATCTAGTGAATCATGGCGAGCCCGGAAGAGAGGCTCCTAGACGAGCTCAATAACGTAATTGTGTCATTTCTGTGTGAC
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
41581715/41185711 (Hg38)
End
41581715/41185711 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
EP300-AS1
Nearest miRNA
hsa-mir-1281/Upstream/93145; hsa-let-7a-3/Downstream/67281;
Nearest TSS
ENST00000624155/Upstream/2567; ENST00000453659/Downstream/11745;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/92556, chr22-CpG: 95/Downstream/11308
Upstream sequence
ctgtctcaaaaaaaaaaaaaaaaaaagaataaaGCTGGAggccaggcacggtggctcacgcctgtaatcccagcactttgtagggcagaggcgggcagat
Downstream sequence
cacttgaggtcatgagttcgagaccagcctggccaacatggtgaaaccccgtctctactaaaaatttaaaaattaccatagtgatggggcctgtaatccg
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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