Basic Information
VIS ID
TVIS42000206
Fusion event
EBV-GUCA1C integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
102788
Orient
+
Integrated sequence
CCAGAACATTTTCATGTGCTACCGCACGCTGGAGCATGCCAAGATCTGCCAGCTCCTGAACACGGCCCCTCTCAAGGCCATCGTGGGCCACGGGGGGCGA| |GACATGTACAAGGACATCCTGGCCCATCTGGAGCAGAACTCACAGCGCAAGGACCCCAAGAAGGAGCTGCTGAACCTGCTGGTCAAGCTCTCGGAGAACA
Host Sequence
Chromosome
chr3
Cytoband
q13.13
Reference genome
GRCh37/hg19
Start
108633092/108914245 (Hg38)
End
108633092/108914245 (Hg38)
Orient
-
Location type
Intronic
Target gene
GUCA1C
Nearest miRNA
hsa-let-7g/Upstream/5390129; hsa-mir-12124/Downstream/688583;
Nearest TSS
ENST00000440867/Upstream/91386; ENST00000480826/Downstream/39517;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/324488, chr3-CpG: 28/Downstream/203703
Upstream sequence
AGAGGAAAGCTACAGGAAAATGTTTCTATTGCACTCTCTTCTTCCCTGTCCCCAGACTTTTCCTGAATCACTCATAATCCCTTTACCTATATTCTTTTTT
Downstream sequence
TTCTCTTTTCTGAATTCACGTCTCTTTTAACCCAGCCCTTTCTACTTCAAGTTCCTTTCTAATCACAGTCCCCATTTTATCGATTCCTTATACTTTGCCC
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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