VISDB Viral Integration Site DataBase

VIS ID

TVIS42000207

Fusion event

EBV-PHLDB2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

72272

Orient

+

Integrated sequence

TGTGTAGTAGAGTACCAGAAACACCCTCACATTCTTGGAGCTGGCCCTGTGGGTATGCCTCAGGCACGCAAAGTTCCTGCCCCGGGCATGGCACACCTGA| |ACTAAGTTTGGCCCGGTTTGCTCAAACGTGACATGGAGAAACTGGGGGAATTTGTCTTCTGGCACAGCTGTTGCCAGGGTGCTCATGAGCGAGGGCCAGA

Chromosome

chr3

Cytoband

q13.2

Reference genome

Start

End

111583980/111865133 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-1-3p ; hsa-mir-432-5p ; hsa-mir-376a-5p ; hsa-mir-382-3p ; hsa-mir-29c-3p ; hsa-mir-148a-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-202-5p ; hsa-mir-298 ; hsa-mir-4709-3p

Nearest miRNA

hsa-let-7g/Upstream/2262236; hsa-mir-12124/Downstream/247668;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/5241, chr3-CpG: 40/Downstream/113759

Upstream sequence

acacTAATGGCAATACTCTTGGACAAATGATAGTTGCTTTTTTTTTTTTTTTTTCATGGAAAGAAGGAGGTTTAGTTTACAGATGTTTGAACCAGCTTAA

Downstream sequence

CAGAGGGGATTGAGAAGTGATGTCTGGCTGCCTCACTGCTTACGTCATTGCAGAAGTAGCTTTTCAAAAACAGCTTAAGATTTATTAAGGAAACTGCAAG