Basic Information
VIS ID
TVIS42000216
Fusion event
EBV-PLD1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
9109
Orient
+
Integrated sequence
GACCCTTTTACTAACCCTAATTCGATAGCATATGCTTCCCGTTGGGTAACATATGCTATTGAATTAGGGTTAGTCTGGATAGTATATACTACTACCCGGG| |AAGCATATGCTACCCGTTTAGGGTTAACAAGGGGGCCTTATAAACACTATTGCTAATGCCCTCTTGAGGGTCCGCTTATCGGTAGCTACACAGGCCCCTC
Host Sequence
Chromosome
chr3
Cytoband
q26.31
Reference genome
GRCh37/hg19
Start
171342976/171625186 (Hg38)
End
171342976/171625186 (Hg38)
Orient
+
Location type
Intronic
Target gene
PLD1
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-638 ; hsa-mir-182-5p
Nearest miRNA
hsa-let-7g/Upstream/518427; hsa-mir-1224/Downstream/3744354;
Nearest TSS
ENST00000440867/Upstream/22848; ENST00000619900/Downstream/17968;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/164011, chr3-CpG: 84/Downstream/184641
Nearest cancer related gene
PLD1(TSG, No orient, 0)
Upstream sequence
gtcttctgcaagcaggggcaatttgacttcctcttttcctaattgaatgccctttatttccttctcctgcctgattgccctggccagaacttccaacact
Downstream sequence
caccaggagattatatcccgcacatggcttggaggctcccacgcccacggagtctcgctgattgctagcacagcagtctgagatcaaactgcaaggtggc
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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