VISDB Viral Integration Site DataBase

VIS ID

TVIS42000219

Fusion event

EBV-ST6GAL1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

136911

Orient

+

Integrated sequence

TGCCTCCTTACTACGGATCCCACTTGCGGGCAGACTACGTCCCCGCTCCCTCGCGATCCAACAAGCGGAAAAGAGACCCCGAGGAGGATGAAGAAGGCGG| |GGGGCTATTCCCGGGGGAGGACGCCACCCTCTACCGCAAGGACATAGCGGGCCTCTCCAAGAGTGTGAATGAGTTACAGCACACGCTACAGGCCCTGCGC

Chromosome

chr3

Cytoband

q27.3

Reference genome

Start

End

186750323/187032535 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-492 ; hsa-mir-335-5p ; hsa-mir-21-5p ; hsa-mir-18a-3p ; hsa-mir-218-5p ; hsa-mir-8081 ; hsa-mir-384 ; hsa-mir-3685 ; hsa-mir-627-5p ; hsa-mir-937-5p ; hsa-mir-526b-5p ; hsa-mir-924 ; hsa-mir-5009-3p

Nearest miRNA

hsa-let-7g/Upstream/245758; hsa-mir-28/Downstream/1656246;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/101221, chr3-CpG: 63/Downstream/106604

Upstream sequence

TTTAAGAAATTATCATTGAGAATAACGTTTTTGCAAAATGTCCTTTTGAGAAATCATGAATTAAATGGCTTATCACAGATCTAAATTATCAGAAGCATTA

Downstream sequence

agagatactccctggaaataatagagaagaaggttgacaagattcctatttatgaagcttatatttttagtggaaggagacagactaatcaaatactaaa