VISDB Viral Integration Site DataBase

VIS ID

TVIS42000221

Fusion event

EBV-PAK2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

129530

Orient

+

Integrated sequence

CTGGGTAGTCACGTTCAGCCGCAACTCGCGTAGCACCACGTGGCTGCCGATAAACAGGGTCTCTCTCATCACGGTATGCAGGGGCTGGAAAAGGGGGTGG| |CGGTTGTAGGCCGAGAGAAGCACAGATGTGGCGCCTCCAATGAGGCCACTGTAAACCCCGGCCTTGGGGTAGCCGACGGTGGCTAACCTCAGCGCGTACT

Chromosome

chr3

Cytoband

q29

Reference genome

Start

End

196470146/196743275 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-500a-3p ; hsa-mir-193b-3p ; hsa-mir-15a-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-298 ; hsa-mir-922 ; hsa-mir-548e-5p ; hsa-mir-1253 ; hsa-mir-4311 ; hsa-mir-6838-5p ; hsa-mir-944 ; hsa-mir-3120-3p ; hsa-mir-3163 ; hsa-mir-4698 ; hsa-mir-5692a ; hsa-mir-8063 ; hsa-mir-3133 ; hsa-mir-3925-5p ; hsa-mir-8084 ; hsa-mir-302a-3p ; hsa-mir-302b-3p ; hsa-mir-302c-3p ; hsa-mir-302d-3p ; hsa-mir-372-3p ; hsa-mir-373-3p ; hsa-mir-520e ; hsa-mir-520f-5p ; hsa-mir-519c-3p ; hsa-mir-520a-3p ; hsa-mir-519b-3p ; hsa-mir-520b ; hsa-mir-520c-3p ; hsa-mir-520d-3p ; hsa-mir-519a-3p ; hsa-mir-302e ; hsa-mir-4799-5p ; hsa-mir-224-5p ; hsa-mir-218-5p ; hsa-mir-1273e ; hsa-mir-636 ; hsa-mir-648 ; hsa-mir-4773 ; hsa-mir-595 ; hsa-mir-658 ; hsa-mir-219b-3p ; hsa-mir-6840-3p ; hsa-mir-7846-3p ; hsa-mir-302f ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-625-3p ; hsa-mir-429 ; hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-6502-5p ; hsa-mir-1301-5p ; hsa-mir-4786-5p ; hsa-mir-4307 ; hsa-mir-6502-3p ; hsa-mir-6512-5p ; hsa-mir-4646-3p ; hsa-mir-4433b-5p ; hsa-mir-580-3p ; hsa-mir-1287-3p ; hsa-mir-7976 ; hsa-mir-4766-5p ; hsa-mir-345-3p ; hsa-mir-6779-3p ; hsa-mir-4687-5p ; hsa-mir-129-1-3p ; hsa-mir-129-2-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-134-5p ; hsa-mir-137 ; hsa-mir-1273g-3p ; hsa-mir-3160-3p ; hsa-mir-4487 ; hsa-mir-4793-3p ; hsa-mir-558 ; hsa-mir-5694 ; hsa-mir-668-3p ; hsa-mir-6890-3p ; hsa-mir-7703 ; hsa-mir-96-3p

Nearest miRNA

hsa-let-7g/Upstream/860880; hsa-mir-4797/Downstream/550603;

Nearest TSS

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/2793, chr3-CpG: 101/Downstream/124430

Upstream sequence

gccgccgggccgcagggcacggggccggcgcggggggggagcggagaggggctggggagccccaggggtccggggcccgcccgcgggggatgggcaggga

Downstream sequence

AGTACTTACTCCATGTATCCcatgtggttaggagctagagtcctgcgtttgaattcttgctgttctactttaccctgggcaagatatacattcttttcaa