VISDB Viral Integration Site DataBase

VIS ID

TVIS42000227

Fusion event

EBV-EPHA5 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

44302

Orient

-

Integrated sequence

TGCAGATCTCGCAGTGAGACCCCAGAGTCAGGCTGTGGCCGAAGGGAGACAGGCGAAGGCAGCGCCCGGGGGAGAGAGTGCACAGTGACAGTGGGAGAAA| |CACGGCCTCTGAGACATGTATGGGGGTGTTCATCTCACGCAGAAAATCTTTGCCCAGCTCAAAGTTGGCAGAGATTCCCCTGAAGAAGTCCCGTAGTGAA

Chromosome

chr4

Cytoband

q13.1

Reference genome

Start

End

66289878/65424160 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-181a-5p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-5010-3p ; hsa-mir-147a ; hsa-mir-6818-5p ; hsa-mir-297 ; hsa-mir-190a-3p ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-511-3p ; hsa-mir-5011-5p

Nearest miRNA

hsa-mir-12113/Upstream/4501476; hsa-mir-1243/Downstream/852664;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/2074294, chr4-CpG: 32/Downstream/245315

Upstream sequence

TTGAAATGGTGTGTCTTTTCCAAACACATTTATCTTATATGAAATGCCTTAAATGCATCCACATTATTTTTCCAACTTAACCATAACATTCTAGTTTTTT

Downstream sequence

TGTTTGACTTATTGATAATGATATAATGTAGAAACCTCTAATATCCCAATGACACAAACAATGATATCAATGATATACAAAATCCTGTCATCAGTTGTAT