VISDB Viral Integration Site DataBase

VIS ID

TVIS42000229

Fusion event

EBV-WDFY3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

156812

Orient

+

Integrated sequence

ACAAACCCCCCACCGTGCTGACTAGGTTGGTGATGGACTGACCCACGCTACCCAGACTGTCCATAAGTTCCCCCAGGCCGTCCACGAATTGATTTCTTCC| |GTTTGACACTGCATTGTCCAAATCCTTCCGCAGGCCGGCGATGTTTTGCGCCTGGAAGTTGTACTCCCGGAAGATGCCCTCCAGGTCAAAGACGTTGGAG

Chromosome

chr4

Cytoband

q21.23

Reference genome

Start

End

85667530/84746377 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-19a-3p ; hsa-let-7e-5p ; hsa-mir-144-5p ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-3942-3p ; hsa-mir-4262 ; hsa-mir-4494 ; hsa-mir-4704-5p ; hsa-mir-5100 ; hsa-mir-543 ; hsa-mir-8064 ; hsa-mir-892c-5p

Nearest miRNA

hsa-mir-12113/Upstream/1992947; hsa-mir-1243/Downstream/976091;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/162637, chr4-CpG: 117/Downstream/219278

Upstream sequence

AACAAACATCACTCAGGGAGCAGGTGTCCTCTCCGTTCCCTCTGCCAGCTTTCTGCCCGCTGCCAAGCCTGTAGTTCTATCTGGATATGTTAGCTGTGCA

Downstream sequence

ATGAGTAGGGCTTATCAAATCTTAACTAGAAAAAGTTTTGAAGTCTGTAAAACAAAGGGACTATTAAACGTACAGAAATGCTTGGTGAATAACatttatt