Basic Information
VIS ID
TVIS42000231
Fusion event
EBV-DKK2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
100663
Orient
-
Integrated sequence
TTTTGGTCTTGCAGTTGACCGACACCGAGCTGTGCTTGACGTAGGTGACATTGTAGGTGACCTTGACCCGTTCTTCGTCCTGCTCGGTGCCCACCGGGAC| |CATGTCTTGGTCGGCGAACTGCGAGTAGTTACCGAGGCGTGCATAATTCTTTTGGAGCCAGGTGTGGGCCGTGAGGCCCGGAAGCCCGACCAGGGTCTTG
Host Sequence
Chromosome
chr4
Cytoband
q25
Reference genome
GRCh37/hg19
Start
107845855/106924698 (Hg38)
End
107845855/106924698 (Hg38)
Orient
+
Location type
Intronic
Target gene
DKK2
miRNAs that regulate target gene
hsa-mir-221-3p ; hsa-mir-218-5p ; hsa-mir-335-5p ; hsa-mir-222-3p ; hsa-mir-1260b ; hsa-mir-27a-3p
Nearest miRNA
hsa-mir-12113/Upstream/5594284; hsa-mir-1243/Downstream/2564000;
Nearest TSS
ENST00000502981/Upstream/491074; ENST00000508555/Downstream/111114;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/1028086, chr4-CpG: 61/Downstream/110700
Upstream sequence
GGCTTGATTTTTCCATAATTTAGGGAAAGTAATCAAGGCTGGGAATGTATTTTGGGTTGAAGTGTGACATGTCTCAGACTGTCTCTAACTGCCAAGTGGT
Downstream sequence
GCCTGGAGATGATCATATAATCAGTTAGACTAATTCAATTCTATGAAATGTGATACTTATCCACATACTCTCTTGATGTGAAATATGAAGCCatttatct
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate