Basic Information
VIS ID
TVIS42000239
Fusion event
EBV-NOCT integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
84583
Orient
+
Integrated sequence
CAGGCCCCCACAGTGGTCCTCCAGCGACCACCCACGCAGCAAGAGCCTGGCCCCGTCGGCCCACTGAGTGTCCAGGCTCGGCTGGAGCCATGGCAACCTT| |TGCCTGGGCCCCAAGTGACAGCAGTTCTACTTCACGAAGAATCCATGCAGGGTGTCCAAGTACATGGTTCGATGCTAGACCTTCTTGAAAAAGACGATGA
Host Sequence
Chromosome
chr4
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
139942810/139021656 (Hg38)
End
139942810/139021656 (Hg38)
Orient
-
Location type
Intronic
Target gene
NOCT
miRNAs that regulate target gene
hsa-mir-296-3p ; hsa-let-7e-5p
Nearest miRNA
hsa-mir-12113/Upstream/13514349; hsa-mir-1305/Downstream/4321804;
Nearest TSS
ENST00000502981/Upstream/5860; ENST00000515616/Downstream/21416;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/5382, chr4-CpG: 18/Downstream/61258
Upstream sequence
ACTCATTGAAAAACAGCAACAAAGATGAGTTCCAGTGACTCATCTTCTGTGGACTTTCTCCAATGTAGTAATGCTCTTGGAAGGAGTTACATTAACTATT
Downstream sequence
AAAAGAAAAGTGAGGTAATTGTGTTCTGGCTTCTTGGAGTTAGGAAGGGAGATACAGCGTCTGTATTTGCTGTCAGGAGTCACTGGTGACTAATTACAGt
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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