Basic Information
VIS ID
TVIS42000244
Fusion event
EBV-CTNND2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
79648
Orient
+
Integrated sequence
ATAGTTAGAGCCAATTCTCCTGCACCAAGGAGCTCCAGTAGAAAGAGATTGGTGGCATTTTCTGAGCCACCAAATGCACCTCGAGGTTGGTAGACAGCCT| |TCGTATGGGGTGTCAGCTGGCCAAAGTCAAGATCAAGTTGATGCTTTTTGCCCCCGACATCGAAATTGATAGTTACATTGACATCTGCCGTGCAAACATT
Host Sequence
Chromosome
chr5
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
11032361/11032249 (Hg38)
End
11032361/11032249 (Hg38)
Orient
+
Location type
Intronic
Target gene
CTNND2
Nearest miRNA
hsa-mir-10397/Upstream/554104; hsa-mir-103a-1/Downstream/3793680;
Nearest TSS
ENST00000502646/Upstream/14189; ENST00000505877/Downstream/85243;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/270436, chr5-CpG: 115/Downstream/352320
Nearest cancer related gene
CTNND2(OG, No orient, 0)
Upstream sequence
ccatgtgaagattaagtgcattatgaaaaagtactcagtgactcatcaagtggaactagtggcaaaaaatattgatatcaaagatgcatataaagaattc
Downstream sequence
GGATGTCTGTAAGTTAGTGTGAAAAGGATTAAAGGGTTTTTTTCCTTTTGTATATAAAAGGTTGTTTGATGTTTACAATGCTGGAATGTTTTGTCTCTCA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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