VISDB Viral Integration Site DataBase

VIS ID

TVIS42000248

Fusion event

EBV-OSMR integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

151962

Orient

+

Integrated sequence

TCTGTGCAATCAAACCCCAGGCTCCCGGCCTCACCCAGGAAGAGCAGCGGCAGGGACAGCATAAACCAGGAGAAGGCGCAAATGAGTCCGGTGAAGGTGA| |CGTTGCATATCAGGCGCGGCTTCCTTCCGAATTTTGTGCGCAAAAGTTTCCAGATGATGATAACTGTGAGGAGGACGATCAGGACTGCCGCCAGTAGGTA

Chromosome

chr5

Cytoband

p13.1

Reference genome

Start

End

38927968/38927866 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-653-3p ; hsa-mir-4420 ; hsa-mir-181b-3p ; hsa-mir-181b-2-3p ; hsa-mir-1208 ; hsa-mir-6760-3p ; hsa-mir-1183 ; hsa-mir-100-3p ; hsa-mir-450a-2-3p ; hsa-mir-6857-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6810-5p ; hsa-mir-2110 ; hsa-mir-7977 ; hsa-mir-6780b-5p ; hsa-mir-4271 ; hsa-mir-4725-3p ; hsa-mir-3189-3p ; hsa-mir-1228-3p ; hsa-mir-129-2-3p ; hsa-mir-129-1-3p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-342-3p ; hsa-mir-3622b-5p ; hsa-mir-6516-5p ; hsa-mir-1273e ; hsa-mir-455-3p ; hsa-mir-6807-5p ; hsa-mir-25-5p ; hsa-mir-658 ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-6087 ; hsa-mir-4725-5p ; hsa-mir-219b-3p ; hsa-mir-3192-5p ; hsa-mir-6791-5p ; hsa-mir-4292 ; hsa-mir-4459 ; hsa-mir-504-5p ; hsa-mir-302f ; hsa-mir-767-5p ; hsa-mir-3130-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p

Nearest miRNA

hsa-mir-10397/Upstream/370305; hsa-mir-103a-1/Downstream/15023638;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/81492, chr5-CpG: 139/Downstream/145913

Upstream sequence

TGGCACAGAAAATGAGAGGAATTAAAATCTTGGGTTCACACACTCTCTCATATTGGTCTTTGCATGGTCTCCTTTTATTCTGCTAGTCAGTTCGTTAATC

Downstream sequence

cttcctcttgaatgcttttctctgtagaaatttcttctgccagataccctaaatcatctgtctcaagttcaacgttccacagatctctagggcaggggca