VISDB Viral Integration Site DataBase

VIS ID

TVIS42000264

Fusion event

EBV-LYRM7 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

68978

Orient

+

Integrated sequence

TCGGCCTCCTGGCCAGCACCCCCTTCATTTGGTGCTTTGTCTTTGCCAACCTGCTCTCTCTGGAGATCTTCTCACCGTGGCAGACACACGTGTACAGGCT| |TGGATTCCCGACGGCATGCCTAATGGCCGTCCTCTGGACGCTGGTACCCGCCAAGCACGCGGTGAGGGCCGTCACTCCAGCCATCATGCTGAATATTGCC

Chromosome

chr5

Cytoband

q23.3

Reference genome

Start

End

130521274/131185581 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-30e-5p ; hsa-mir-590-3p ; hsa-mir-4775 ; hsa-mir-574-5p ; hsa-mir-2113 ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-411-5p ; hsa-mir-6832-5p ; hsa-mir-193b-5p ; hsa-mir-1273f ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-4735-5p ; hsa-mir-6890-5p ; hsa-mir-7851-3p ; hsa-mir-619-3p ; hsa-mir-6867-5p ; hsa-mir-892a ; hsa-mir-548g-3p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-3941 ; hsa-mir-4719 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3646 ; hsa-mir-223-5p ; hsa-mir-3713 ; hsa-mir-6870-3p ; hsa-mir-6891-3p ; hsa-mir-6072 ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-501-5p ; hsa-mir-1305 ; hsa-mir-1468-5p ; hsa-mir-498 ; hsa-mir-6783-3p ; hsa-mir-1343-3p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6852-5p ; hsa-mir-939-3p ; hsa-mir-6827-3p ; hsa-mir-340-3p ; hsa-mir-3978 ; hsa-mir-6124 ; hsa-mir-3148 ; hsa-mir-432-5p ; hsa-mir-3686 ; hsa-mir-4715-3p ; hsa-mir-1227-3p ; hsa-mir-4742-3p ; hsa-mir-6765-3p ; hsa-mir-4778-5p ; hsa-mir-1228-3p ; hsa-mir-5571-5p ; hsa-mir-455-5p ; hsa-mir-629-3p ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-5587-5p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-6801-5p ; hsa-mir-6131 ; hsa-mir-3663-5p ; hsa-mir-150-5p ; hsa-mir-136-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-4716-5p ; hsa-mir-484 ; hsa-mir-3155b ; hsa-mir-3155a ; hsa-mir-4781-3p

Nearest miRNA

hsa-mir-10397/Upstream/1788434; hsa-mir-103a-1/Downstream/1032268;

Nearest TSS

Nearest CpG islands

None/Target, chr5-CpG: 87/Upstream/14488, chr5-CpG: 110/Downstream/78061

Upstream sequence

atcctctaaggatggacgccatggggctctgtcccctttcttctccttccgacttcctgctggctggaaggtgagcattttggcggaggctgaagtgtca

Downstream sequence

tcattacatatttttaaattatatctatcaatactaatatccatctcatcagaaaaatctttaaggctgggcatggtggctcacacctgtaatcccaaca