Basic Information
VIS ID
TVIS42000268
Fusion event
EBV-RANBP17 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
149470
Orient
+
Integrated sequence
GCTCAGGGGGGCCTCGTAGGTGTTGTTGTATTCCAGCTCCGTGATGAAATTAGGAGGAATAATCACAGGGGAGCCAAAGTAGCGGATGTCTGTGGATTCC| |CCGTCCCAGCGCCAGTGGCTCTTAGGGTAGGGGTTGTAACGGAAGGCAATAATCACATCATCCAATAGGGTCATGCCCACCTTGACGTTCAGCGGGCCCT
Host Sequence
Chromosome
chr5
Cytoband
q35.1
Reference genome
GRCh37/hg19
Start
170599952/171172948 (Hg38)
End
170599952/171172948 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
RANBP17
miRNAs that regulate target gene
hsa-mir-361-5p
Nearest miRNA
hsa-mir-10397/Upstream/1144382; hsa-mir-10523/Downstream/213708;
Nearest TSS
ENST00000502646/Upstream/29627; ENST00000521834/Downstream/68085;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/310305, chr5-CpG: 417/Downstream/135217
Upstream sequence
GAGGTCTGGAGGAATTGGCTGAAAAAACAGGGTGAACTAGGAGCTAAGCAGGCCCAttctttttttttttttttttttttttttttttttttttAccttc
Downstream sequence
TTACTAGATAAAAGTTTAAAAGCTATAATATTTTAAGCCAGGGGATAGGAATGATTTCAACATGGGTACATTGATTTATATTTTTTAGCAATTATTTCAG
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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