Basic Information
VIS ID
TVIS42000272
Fusion event
EBV-KHDRBS2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
84233
Orient
-
Integrated sequence
AGATTGATCTGGCCTATGCCCGCGGGCAGGCCATGAATATTGAGGCTCCTAGACTGCCAGATGATCCTATAATTGTTGAGGATGACGACGAAAGTGAGGA| |AATTGAAGCTGAAAGCGACGAGGAGGAAGACAAGAGTGGAATGGAATCTCTTAAAAATATACCGCAAACACTGCCGTACAATCCAACAGTATACGGCAGG
Host Sequence
Chromosome
chr6
Cytoband
q11.1
Reference genome
GRCh37/hg19
Start
62579872/61869967 (Hg38)
End
62579872/61869967 (Hg38)
Orient
+
Location type
Intronic
Target gene
KHDRBS2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-10398/Upstream/4479755; hsa-mir-10524/Downstream/9506993;
Nearest TSS
ENST00000381078/Upstream/1146819; ENST00000370659/Downstream/416260;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/3908417, chr6-CpG: 45/Downstream/415983
Upstream sequence
TCATGAGTTAGATGAGAGTGTTTAGTGGGAAGTGAAAAGACCCGTCCACGGTTTCGGATGAGATCCTCGTTGGACTGTGATCCCAGGATATTACCCAGGC
Downstream sequence
ttttttttttttttttttttccccatactacagtggtgcctggaatgccagtgagacagaagtgttccctccccaggaaaggggtggggctgaagccagg
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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