Basic Information
VIS ID
TVIS42000274
Fusion event
EBV-EYS integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
133553
Orient
-
Integrated sequence
GGGCGCTCTGCGCCAGCCCCGCCCTCCCCATCCCCAGCCCAGCCGTTCACTCGGCTCACCGGGAACGCCCAGTATGCAGTCTCAATCTCTCCCACGGACC| |CCCCTCTGATGGTGGCCGGCAGCCTGGCTCAAACGCTGCTTGGTAATCTGTACGGGAACATCAACCAGTGGGTACCGTCCTTCGGACCCTGGTACAGGAC
Host Sequence
Chromosome
chr6
Cytoband
q12
Reference genome
GRCh37/hg19
Start
66279054/65569161 (Hg38)
End
66279054/65569161 (Hg38)
Orient
+
Location type
Intronic
Target gene
EYS
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-510-3p ; hsa-mir-376a-5p ; hsa-mir-4680-5p ; hsa-mir-494-3p
Nearest miRNA
hsa-mir-10398/Upstream/8178949; hsa-mir-10524/Downstream/5807799;
Nearest TSS
ENST00000381078/Upstream/73163; ENST00000449928/Downstream/138053;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/267573, chr6-CpG: 34/Downstream/218621
Upstream sequence
GCTGTGCCCTCCTCAGAGAAGCTCAGCAGAGTTTGACACAGCTGCCCTTGTCTTCCTTCAGGAGCACCTGGTTCCTCTGGCGTCTGGGGTCCCCCCCTCC
Downstream sequence
tccttctcctggctcatcccggctcaaaagctcccccactgagcaccttgtgacccccgcccctgcccagggagaactaccccctttgactgtaattttc
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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