Basic Information
VIS ID
TVIS42000278
Fusion event
EBV-ASCC3 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
166089
Orient
-
Integrated sequence
CCGCGGTTTCAGCATCACAGGTTATTTTGCCTGAAGCTTGCTGGGGCGTAAATCCCTCTCGCCTTGTTTCTCAGAGAGCATTTCAGGCCGGTTTTGCAGT| |CGCTGCTGCAGCTATGGGGTCCCTAGAAATGGTGCCAATGGGCGCGGGTCCCCCTAGCCCCGGCGGGGATCCGGATGGGTACGATGGCGGAAACAACTCC
Host Sequence
Chromosome
chr6
Cytoband
q16.3
Reference genome
GRCh37/hg19
Start
101109756/100661880 (Hg38)
End
101109756/100661880 (Hg38)
Orient
+
Location type
Intronic
Target gene
ASCC3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-98-5p ; hsa-mir-30a-5p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-1226-3p ; hsa-mir-425-5p ; hsa-let-7f-5p ; hsa-let-7a-5p
Nearest miRNA
hsa-mir-10398/Upstream/1537184; hsa-mir-1202/Downstream/6122245;
Nearest TSS
ENST00000381078/Upstream/151572; ENST00000565695/Downstream/219421;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/192233, chr6-CpG: 68/Downstream/218991
Upstream sequence
CCACCAGTGCACCTGAGGCATTCTGAGGACGGTGCTGCAGGGGTTATTTTAGGGATGTAGACTCAGCtttttttttttttttttttttttttttttcccg
Downstream sequence
GTAATGGCTGAGTTTATCATGCGTTGTTATAATTATTCCTTCCCCAAATTTGTCAAATTGTGGTCGTCCAGCTCGACCAAATATCTGCATGACATCTAAA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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