VISDB Viral Integration Site DataBase

VIS ID

TVIS42000280

Fusion event

EBV-FIG4 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

154358

Orient

+

Integrated sequence

TGCTGCTTGTCGAGGATGGTCCTTTGGCGCGGATCCTCGCAGGCCGCCAGCAGCTTCTTGATGGCCTTGCGCTTGGCCAGCCAGGAGGTCAACAGACTAG| |CCAAGAAGGACTCGTGCACGTGCTTCTTTACAAAGTGGTAGACGCCCCCCGTGAGCCTGAAGGACTCATAGTCTTCTCCCGGGCGCAGGCCGGCTAGCCT

Chromosome

chr6

Cytoband

q21

Reference genome

Start

End

110097288/109776085 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-1-3p ; hsa-mir-26b-5p ; hsa-mir-5089-5p ; hsa-mir-7151-3p ; hsa-mir-6807-5p ; hsa-mir-5095 ; hsa-mir-4252 ; hsa-mir-6889-3p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-6849-3p ; hsa-mir-6504-3p ; hsa-mir-4438 ; hsa-mir-6876-5p ; hsa-mir-4476 ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-377-3p ; hsa-mir-6884-3p ; hsa-mir-744-3p ; hsa-mir-106a-3p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-498 ; hsa-mir-4279 ; hsa-mir-6778-3p ; hsa-mir-1976 ; hsa-mir-3653-5p ; hsa-mir-325 ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-4778-3p ; hsa-mir-6787-3p ; hsa-mir-1284 ; hsa-mir-545-3p

Nearest miRNA

hsa-mir-10398/Upstream/2991865; hsa-mir-1202/Downstream/9292962;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/84519, chr6-CpG: 143/Downstream/202077

Upstream sequence

ATGACCAGCGCAGGATGTCATTGCATCTACATGGAGCAGATTGTGATCCTAAAACACAGAATGAAATGAATATATGTGAAGAAGAATTTGTAGAGTATAA

Downstream sequence

GAAAGAAGGAAACGAGGAGAAAGAACGAAGGACACTAGGGAGGAGAATGTAGAATGGGATGGGTGGTTCATGAGACCACTTCAGTGCATATTATCATTGT