Basic Information
VIS ID
TVIS42000286
Fusion event
EBV-LRP11 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
49010
Orient
-
Integrated sequence
AATCCGGGCAGTGCTGCCGCACAACGCGGCCTACGAGCTCGACCGTGGCTCCCGCCTCTTGGATGCCATCATCCCCTGCTTGGGACCCGACCGCACTTGC| |ATGCGGCCGGTGGTCCTGCGGGGGGTGACGGTCAGGCAGCTCCTGTATTTAACTTTGCGGACAGAGGCCAGAGCCGTTTGCTCCATCTGTCAGCAACGCC
Host Sequence
Chromosome
chr6
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
150173162/149852026 (Hg38)
End
150173162/149852026 (Hg38)
Orient
+
Location type
Intronic
Target gene
LRP11
miRNAs that regulate target gene
hsa-mir-122-5p ; hsa-mir-455-3p ; hsa-mir-425-5p
Nearest miRNA
hsa-mir-10398/Upstream/9168143; hsa-mir-1202/Downstream/1250649;
Nearest TSS
ENST00000381078/Upstream/15827; ENST00000472053/Downstream/436;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/101877, chr6-CpG: 167/Downstream/11182
Upstream sequence
ggctacatgatcttaagcaagttagttagcctctgtttacttatctttttaaaataaagtaaatctttcaaatgatgttattataacgattaGCATTTTG
Downstream sequence
gggtgactgcctccataattcagtaacctccacctggtctctcccttgacacgtggagattatggggattacaattcaagatgagatttttgggtgggga
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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