VISDB Viral Integration Site DataBase

VIS ID

TVIS42000287

Fusion event

EBV-MTHFD1L integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

111467

Orient

+

Integrated sequence

GCCTCAAGCTCCTGCTCACGGAGCTCCTCCACCCGCTCTAGCTGCTTGTAGTTGATTTTTGGAAATTGAGTCTTGGTCGCGGTGACCACCCTCTGATAGG| |TAGAAATTAGCTGTTTGGACTCAAACGTCTCCCTTGCGTGGCGCAGGGACTCTAAGGCACCCCGAGCAGATGTAAACTGTGTTTCAAACAGAGCGTGGTC

Chromosome

chr6

Cytoband

q25.1

Reference genome

Start

End

151233970/150912834 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-887-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-218-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-564 ; hsa-mir-3622a-5p ; hsa-mir-29b-2-5p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-92a-1-5p ; hsa-mir-138-5p ; hsa-mir-6131 ; hsa-mir-133a-5p ; hsa-mir-6509-3p ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-508-5p ; hsa-mir-3145-5p ; hsa-mir-4760-3p

Nearest miRNA

hsa-mir-10398/Upstream/10228951; hsa-mir-1202/Downstream/189841;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/45858, chr6-CpG: 25/Downstream/178033

Upstream sequence

AATAGCCAAACTGTTAGGTGAAGCAAGACTGACATGCCCTATAATTTTCTGCATTAGTCATAAATTTAAGGTCATTATTACTCTCTTTGAAATTAGCCAG

Downstream sequence

CCAGATCGTAGACAACCTCCCAATGGAGTCCTGCCCCTACACGGGCAGGGGGTGAAATAATGATTCCCTTTCTTAATTTTCTTTAGCCATGAAATTTATT