VISDB Viral Integration Site DataBase

VIS ID

TVIS42000289

Fusion event

EBV-FSCN1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

11063

Orient

+

Integrated sequence

AAAAAATTTATGGTTCAGTGCGTCGAGTGCTATCTTTGGAACAGTAGAAAATTGAACCTTGTTGGCGGGAGAAGGAATAACGCCTTATCTGGGAGGAGCG| |ACGGATTATAGCCAATAAGAGAGCTCAAGACGCAGGGCTCGCAAAGTATAGTGGCCCCGTGGGACCTTAGAGGTGGAGCAACGTCTAAAGTGGTAATAAC

Chromosome

chr7

Cytoband

p22.1

Reference genome

Start

End

5646403/5606772 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-133a-3p ; hsa-mir-145-5p ; hsa-mir-143-3p ; hsa-mir-133b ; hsa-mir-30a-5p ; hsa-mir-221-3p ; hsa-mir-17-3p ; hsa-mir-6801-5p ; hsa-mir-7162-3p ; hsa-mir-4649-3p ; hsa-mir-6501-3p ; hsa-mir-583 ; hsa-mir-24-3p ; hsa-mir-6792-5p ; hsa-mir-4283 ; hsa-mir-760 ; hsa-mir-5008-5p ; hsa-mir-3663-3p ; hsa-mir-1247-3p ; hsa-mir-7113-5p ; hsa-mir-761 ; hsa-mir-3619-5p ; hsa-mir-214-3p ; hsa-mir-4705 ; hsa-mir-6813-5p ; hsa-mir-6085 ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p ; hsa-mir-6816-5p ; hsa-mir-3196 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-6787-5p ; hsa-mir-6721-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-4749-5p ; hsa-mir-4706 ; hsa-mir-6722-3p ; hsa-mir-1909-3p ; hsa-mir-6802-3p ; hsa-mir-4284 ; hsa-mir-6862-3p ; hsa-mir-6784-3p ; hsa-mir-4707-5p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6837-5p ; hsa-mir-4685-5p ; hsa-mir-5088-5p ; hsa-mir-133a-5p ; hsa-mir-326 ; hsa-mir-429 ; hsa-mir-200b-3p ; hsa-mir-184 ; hsa-mir-185-3p ; hsa-mir-2115-5p ; hsa-mir-299-3p ; hsa-mir-3180-5p ; hsa-mir-3652 ; hsa-mir-3919 ; hsa-mir-4265 ; hsa-mir-4296 ; hsa-mir-4322 ; hsa-mir-4417 ; hsa-mir-4430 ; hsa-mir-4446-3p ; hsa-mir-4489 ; hsa-mir-4492 ; hsa-mir-4498 ; hsa-mir-4505 ; hsa-mir-4533 ; hsa-mir-4656 ; hsa-mir-4673 ; hsa-mir-4681 ; hsa-mir-4722-5p ; hsa-mir-4731-5p ; hsa-mir-4736 ; hsa-mir-4747-5p ; hsa-mir-4770 ; hsa-mir-4804-5p ; hsa-mir-5001-5p ; hsa-mir-501-3p ; hsa-mir-502-3p ; hsa-mir-5196-5p ; hsa-mir-520a-5p ; hsa-mir-525-5p ; hsa-mir-539-5p ; hsa-mir-5787 ; hsa-mir-6088 ; hsa-mir-6746-3p ; hsa-mir-6805-5p ; hsa-mir-6846-5p ; hsa-mir-6848-5p ; hsa-mir-7150 ; hsa-mir-762

Nearest miRNA

hsa-mir-339/Upstream/110855; hsa-mir-10399/Downstream/105068;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/1261, chr7-CpG: 22/Downstream/701

Upstream sequence

CCCACGCCTGGCAGAATCTTCAGTCCTGGCCTAATGAGCTCACCAGCTCAGTAAGTTCTGCGACTGCTTCGGGTTACCAAAAGAATAGAGTATGTAACAG

Downstream sequence

GAGGGAGGCCGTGGCTCCAGTGGGTGCTCCGGAGCTCGTGGGCCCAGCACACCTCCTTAAGCGGGGGATGGAGCGCTGGGAGGGGGTGGACTGTGGCCCA