VISDB Viral Integration Site DataBase

VIS ID

TVIS42000304

Fusion event

EBV-VPS50 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

153540

Orient

+

Integrated sequence

CCTTGGGCTCCACAAAGACGTACTGGATGCGGTCGTGGATCTGGGGCAGTTCCTCGTTGCGCTCGACGAACTTCTGGTAGACGGCCAGGTGAGGCATCTG| |GGTGCTCTTGTAGGCTGAGAGCTTGCGGCTGAGCTCCGTTGAAAAGCAGAGCTCCCCCATGGGGACCCTGCCTTCACGGAGGTCTGTGTAGGCCTGGTTT

Chromosome

chr7

Cytoband

q21.2

Reference genome

Start

End

92865431/93236118 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-127-5p ; hsa-mir-4650-3p ; hsa-mir-3132 ; hsa-mir-197-5p ; hsa-mir-5189-3p ; hsa-mir-4257 ; hsa-mir-6755-5p ; hsa-mir-6847-5p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-335-3p ; hsa-mir-4668-5p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-548z ; hsa-mir-3613-3p ; hsa-mir-548h-3p ; hsa-mir-548bb-3p ; hsa-mir-548d-3p ; hsa-mir-548ac

Nearest miRNA

hsa-mir-10525/Upstream/1032020; hsa-mir-10399/Downstream/246642;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/192416, chr7-CpG: 28/Downstream/338655

Upstream sequence

caaaggtgggaataacctgaatgggtgagctAGCCAGGAAATCTACTGAATTCTAAAGTATTAAACAATTTTTCCTTCTACTGATTAGATTTAGGCTATT

Downstream sequence

gccttgaagccaagtaaagaatttaaaagagtaaggagtgattagctgtgttaaatgctgcagattggtcaagtaaggtgagagtgagaatgagaaatgt