VISDB Viral Integration Site DataBase

VIS ID

TVIS42000306

Fusion event

EBV-LHFPL3 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

118669

Orient

-

Integrated sequence

GTGGTTATAGGGGCGCTAGTCGTGGTCAAGGTCGTAGACTGGTTTGTGCTAGGACCCGATGCCGACGGTGATGGTGTAGTCACAGCCGTTGTGCCTGTCA| |CGTTCCCCGCCGAGGCCGTCGAACTGCCACTAGATGTCCAAATAAGGCTTGTCTCACAGATGAGTATCATGGCCATAACAGCGCCTGCCTTGTCTCTGGC

Chromosome

chr7

Cytoband

q22.2

Reference genome

Start

End

104431837/104791390 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-4709-3p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-4635 ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-1269b ; hsa-mir-1269a ; hsa-mir-4497 ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-5196-5p ; hsa-mir-4271 ; hsa-mir-4747-5p ; hsa-mir-6787-5p ; hsa-mir-663a ; hsa-mir-1908-5p ; hsa-mir-4515 ; hsa-mir-1288-3p ; hsa-mir-4740-5p ; hsa-mir-3202 ; hsa-mir-4749-5p ; hsa-mir-3195 ; hsa-mir-4706 ; hsa-mir-3179 ; hsa-mir-525-3p ; hsa-mir-524-3p ; hsa-mir-342-3p ; hsa-mir-6793-3p ; hsa-mir-574-3p ; hsa-mir-8485 ; hsa-mir-3939 ; hsa-mir-361-3p

Nearest miRNA

hsa-mir-10525/Upstream/2319859; hsa-mir-10399/Downstream/9861955;

Nearest TSS

Nearest CpG islands

None/Target, chr7-CpG: 39/Upstream/461879, chr7-CpG: 45/Downstream/192500

Upstream sequence

tatccaatttcccatgaccatttattgaaaaagactgtcttttcccaaatgtatgctcttggcacctttgttaaaaatcagctagtcataaatatgtgga

Downstream sequence

GCCTTACATTCTTGGGCTGAGATTATTGGTCCCCTACTTAGATGCCCATTCTCCTTTTGCATCACAGACTTCTTGATATTTTTAGCCTCTAACCACATCA