Basic Information
VIS ID
TVIS42000312
Fusion event
EBV-DPP6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
102454
Orient
+
Integrated sequence
CCACCGGCATGGTGCCCGCCGTTAAGAAGCCCATAACCCAAGAGCTCCACTCCAAGATAAAGAGCCTGAGGGACAGGTGCGTCTGTCGGGAATTGGGGCA| |CGAGAGGACCATCAGGAGTATCGGGACGGAATTATATGAGGCAACGAAGGAAATAATAGAGTCGCTCAACTCCACGTTCATCCCCCAGTTTACGGAGGTG
Host Sequence
Chromosome
chr7
Cytoband
q36.2
Reference genome
GRCh37/hg19
Start
153823833/154126748 (Hg38)
End
153823833/154126748 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7I
Target gene
DPP6
miRNAs that regulate target gene
hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-4668-5p ; hsa-mir-3153 ; hsa-mir-513b-3p ; hsa-mir-1276 ; hsa-mir-497-3p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-511-5p ; hsa-mir-6830-3p
Nearest miRNA
hsa-mir-10399/Upstream/2693109; hsa-mir-153-2/Downstream/3447588;
Nearest TSS
ENST00000635602/Upstream/30705; ENST00000462622/Downstream/178362;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/73389, chr7-CpG: 37/Downstream/178131
Upstream sequence
ATGACACCATGTCTCCACCACCTTCCTCCCGGTTATTTATTCACCAAACATGGCATTTAAATAACTCATCTGGAAGTTGATGGTAAGTTCTGTTATTTGA
Downstream sequence
CTAAACAGTTTGCAGACATTAAAAAGGATTTGTATGCCAAGAAGGAGGCCCCTAGCTCATGGGGCCAGCCCCAGTTTGCCTTCCGAATATACTCATTTTG
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate