Basic Information
VIS ID
TVIS42000313
Fusion event
EBV-DPP6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
41781
Orient
+
Integrated sequence
ATGCAGGTCTCCGGGTGGGCAGGCAGTACGAGATGTCACGTTGTGTTGTCTTTCCTCCCACCCCTGTCCTGGCTGTGGCAAATGCGACCCTCATAGAGTT| |GTGTTTCAGGTCTGTGTCCTGTTTTGCGGTGGGTTATTTCTTCCCTCAGTGTTTGCCAGCTTATTTCCCCAGTTTTCACGTACTGGGGCCTGTGGACACC
Host Sequence
Chromosome
chr7
Cytoband
q36.2
Reference genome
GRCh37/hg19
Start
154510368/154718658 (Hg38)
End
154510368/154718658 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7I
Target gene
DPP6
miRNAs that regulate target gene
hsa-mir-6739-5p ; hsa-mir-6733-5p ; hsa-mir-4668-5p ; hsa-mir-3153 ; hsa-mir-513b-3p ; hsa-mir-1276 ; hsa-mir-497-3p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-mir-511-5p ; hsa-mir-6830-3p
Nearest miRNA
hsa-mir-10399/Upstream/3285019; hsa-mir-153-2/Downstream/2855678;
Nearest TSS
ENST00000635602/Upstream/413216; ENST00000478614/Downstream/74936;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/413462, chr7-CpG: 22/Downstream/31691
Upstream sequence
AAGGCAAGTCTTAATTCACCTGATAAATCCTTGTGAAATATGTGTGGAATCTTATGGATTCAGAAAAAGCTGAATTTTTTTTCATTCTTTGTCAATTTAT
Downstream sequence
gactgagttttgctcttgttgcccaggctggagtgcagtggcatgagctcagctcactgcaacctccacctcccagattcaagtgattctccagcctcag
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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