Basic Information
VIS ID
TVIS42000316
Fusion event
EBV-ADAM2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
123779
Orient
+
Integrated sequence
AGCACATTCATGTGATTGGGCCTCCTGTGTTGCAGGGAGTAGGTCTCGCGCCTGTCTCGCGGGGCCGGGGCCGCGTTGAGGCTGTTTAGGGTATGGGCGG| |GTGTGTGGAGTCGGGGGTGACAGAGAACCTTGAGAGCATTCTGTAGGTTAAACGCGAGGAGAAGGTTATTCTTGTTTACGATCCATGCCTCCACCGGTAG
Host Sequence
Chromosome
chr8
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
39690524/39833005 (Hg38)
End
39690524/39833005 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADAM2
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-mir-124-1/Upstream/9875657; hsa-mir-10400/Downstream/1438043;
Nearest TSS
ENST00000518652/Upstream/58303; ENST00000522840/Downstream/5204;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/309991, chr8-CpG: 20/Downstream/1064640
Upstream sequence
caaaataagttaaattgttctatgataacaacttggaaatttctgcattaagaccaaccaacgtctgttgattgttgatgctactcttccaaagcagatt
Downstream sequence
TATTAAACATTTATAAATACTGTATCTGTGATGCAGAAAGTAATTTCAGAGGATGCTTTACTACTGGTCACTGACTTGCTCTCAGTCTCATAACTTGACA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate