Basic Information
VIS ID
TVIS42000319
Fusion event
EBV-PRKDC integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
167308
Orient
+
Integrated sequence
GTTCCTGCCTCTGCTGGCATGAGTTAGGTGTGGCTTGGGCTGAATCCAAATGTGTATTGGCACAAGATGGAAAGCAAAGTTGCTGGAGTTACTGGGTGGG| |AGACAGGGATGTATGTGGTCCCCCGCTGGTATGCCAGTACCCTGTGGAAGTAAGGGGCCTCATCTGCCTGGTAGTTGTGTTGTGCAGAGGTCTGATGTGT
Host Sequence
Chromosome
chr8
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
48816701/47904141 (Hg38)
End
48816701/47904141 (Hg38)
Orient
+
Location type
Intronic
Target gene
PRKDC
miRNAs that regulate target gene
hsa-mir-101-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-124-1/Upstream/5007866; hsa-mir-10400/Downstream/13810647;
Nearest TSS
ENST00000518652/Upstream/39349; ENST00000520994/Downstream/25028;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/72525, chr8-CpG: 36/Downstream/55757
Upstream sequence
tctctacaaaagactttcaaaaaatgagctgcgcatggtagtgtatgtctgtagtcctagctactgatggggccaaggtgggaggattgcttgagcccag
Downstream sequence
GACAATGCTTCTCCGTGTCAGGAGAGTTCTGTGTAAAAGGTGAACTGCTGTTTCCAGGGCCCTTTAGTTATTGAATCTGAGTATAGGAGAAAATTGGATA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate