Basic Information
VIS ID
TVIS42000325
Fusion event
EBV-ZFPM2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
67501
Orient
-
Integrated sequence
TGTATGGCACACCACCCCCCAAGGACTGCCCGCTCACCTACATGACTAGCATCAAGCAAACTAATTTCTTTGAGCAAGAGAGTTCCGATTACACCATGCT| |GGTGGTAGATGACCTTTGAGTCAGGGTGGCTACTTGCTCAGGTTTCTGGGCATAAATTCTCCTGCCTGCCTCTGCTCTGGTACGTTGGCTTCTGCTGCTG
Host Sequence
Chromosome
chr8
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
106671483/105659255 (Hg38)
End
106671483/105659255 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8A
Target gene
ZFPM2
miRNAs that regulate target gene
hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-429 ; hsa-mir-26b-5p ; hsa-mir-184
Nearest miRNA
hsa-mir-12123/Upstream/1174790; hsa-mir-10400/Downstream/6984238;
Nearest TSS
ENST00000518652/Upstream/130371; ENST00000522296/Downstream/26510;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/339363, chr8-CpG: 19/Downstream/556302
Upstream sequence
GGGGTGAAGCTGAAAGGGACAGAGGTGGGTGCAGTCAGCTGCCCTGTCCCCCCACTGCCTGCCCCTGAAGCAACTCAGTGTGTTTTCTTGGTGTGCAGAA
Downstream sequence
AAAAAAAAAGCAAATAAATAATAAAATCCTGAGAAACAAGAAATCATACAGTGAACAGCAATTGGCTGTTATGCCCTAACCTTCAACTCTGAAAGTATGA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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