VISDB Viral Integration Site DataBase

VIS ID

TVIS42000328

Fusion event

EBV-ENPP2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

Nasopharyngeal carcinoma (NPC)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

89385

Orient

+

Integrated sequence

AGTCCCCCCATCTAATGATGTCCAGTTCCCTTCTCCCACCCTGTACACCCCGACCCAAAGGGACTCAATGGCATTCAGATTTCTAGTTACCACAGGTAGA| |ATATCGGGCGTTGGCCCATAAAAATAAGTGCATGGATATAGCTCTGCACAGGCTTGGAAACACCCATTCCAGGTGTGCTTCTTTTTGGTGAAATAAAAAC

Chromosome

chr8

Cytoband

q24.12

Reference genome

Start

End

120649210/119636970 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA8C ; FRA8E

Target gene

miRNAs that regulate target gene

hsa-mir-767-5p ; hsa-mir-17-3p ; hsa-mir-1205 ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-3065-3p ; hsa-mir-4762-5p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-29c-3p ; hsa-mir-29b-3p ; hsa-mir-29a-3p

Nearest miRNA

hsa-mir-12123/Upstream/311705; hsa-mir-10400/Downstream/3578818;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/220032, chr8-CpG: 29/Downstream/195588

Upstream sequence

TGCTTTTCATTGTTTTGTTAAGTCAATGCTTTTTTTTATTTTAATGTATTCTTTTGCCTTTTTCAGTTATGCTCCCTATTCCTTCTAAGTTTTATTGGCT

Downstream sequence

CTCAATTTTACATTCATTAAGGAAACAGCATTTAATTCTTTCAATCTCAGTTTTAGCCAGAGTAATATATTAAGAGGAAACAGAAAAAAAAAGTTCCCTT