Basic Information
VIS ID
TVIS42000330
Fusion event
EBV-COL22A1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
76717
Orient
-
Integrated sequence
TGCTCGTTAAACCAATAGCATGTCAGCTCCACGCAAAGTCAGATTGCCTTCTGTTAAGGCTGTTGACATGAGCATGGAAGACATGGCCGCCCGCCTGGCT| |CGCCTGGAGTCTGAGAATAAGGCTCTGAAGCAACAGGTCCTCAGAGGGGGTGCCTGTGCCTCGTCTACCTCTGTTCCTTCTGCTCCAGTGCCTCCGCCTG
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
139913643/138901400 (Hg38)
End
139913643/138901400 (Hg38)
Orient
+
Location type
Intronic
Target gene
COL22A1
miRNAs that regulate target gene
hsa-mir-5587-5p ; hsa-mir-432-3p ; hsa-mir-4436b-5p ; hsa-mir-197-3p ; hsa-mir-1193 ; hsa-mir-6500-3p
Nearest miRNA
hsa-mir-1204/Upstream/4096455; hsa-mir-10400/Downstream/1831164;
Nearest TSS
ENST00000518652/Upstream/18189; ENST00000518354/Downstream/12593;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/23196, chr8-CpG: 17/Downstream/717453
Upstream sequence
acattgactcctactgggaaaacctaacatccccagataacaacgagaaagtagctatctgtgaaaatgctttgttatttgtggatacatctcacagaat
Downstream sequence
ctatcccctaggctggagtgcagtggtgtgatcacagctcactgcagcctctacctcccaggctctggtgatcctcccacctcagcctcccaggtagctg
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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