Basic Information
VIS ID
TVIS42000333
Fusion event
EBV-MPDZ integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
156952
Orient
+
Integrated sequence
ATGTTTTGCGCCTGGAAGTTGTACTCCCGGAAGATGCCCTCCAGGTCAAAGACGTTGGAGGCACGCTGTTCGTCCCGTGAGTACAGCTCCAGGGAGGCAA| |AGTCAATGTTCTCGATGAGGGAGGTGTTTAGTGAGATGAAGGTCTGCAGGGTGGCAATGCCGTCCAGCTCGATGGTTTTAAAGTGGTGGTAGTCGTTGTA
Host Sequence
Chromosome
chr9
Cytoband
p23
Reference genome
GRCh37/hg19
Start
13247501/13247502 (Hg38)
End
13247501/13247502 (Hg38)
Orient
+
Location type
Intronic
Target gene
MPDZ
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-101-2/Upstream/7239598; hsa-let-7a-1/Downstream/5325804;
Nearest TSS
ENST00000422679/Upstream/27804; ENST00000428006/Downstream/2856;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/471688, chr9-CpG: 144/Downstream/30811
Upstream sequence
TCTCCCGCAGTCTCCACTCCCCACCCCCATGGCTTGCGACGGGTCGCGTATTTGATTACGCAAAGTAAGTTGGGAAATCCTATGTCCGCAATCCCATCTG
Downstream sequence
GGGAGAGAAGTTGCAGGCAGTGGATGATTGGAAAATACCCAGTCGTAGAAGAGGCCAGATGCAAAGATGTTGATGACCTGTGGGTTTCAAGGGCAGGAAC
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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