Basic Information
VIS ID
TVIS42000340
Fusion event
EBV-DDX31 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
Nasopharyngeal carcinoma (NPC)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
4287
Orient
+
Integrated sequence
CAGTGCTTCAGAAGACGGGCAGTCTCCTGATTGCGGTGCGTTGCGGGGATGGCAAGATCCAGGGAGGGTCGCTGTTTGAGCAGCTCTTTAGCGACGTGGC| |CACGACCCCACGGGCACCCGAGGCGTTGTCTCTGAAGAATCTCTTCCGGGCAGTCCAGCAGCTGGTCAAGAGCGGCATCGTGCTGTCAGGGCATGACATC
Host Sequence
Chromosome
chr9
Cytoband
q34.13
Reference genome
GRCh37/hg19
Start
135533440/132658053 (Hg38)
End
135533440/132658053 (Hg38)
Orient
-
Location type
Intronic
Target gene
DDX31
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-877-3p
Nearest miRNA
hsa-let-7a-1/Upstream/2031690; hsa-mir-126/Downstream/287654;
Nearest TSS
ENST00000422679/Upstream/45740; ENST00000483873/Downstream/11974;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/67200, chr9-CpG: 149/Downstream/11603
Upstream sequence
GACCCAGGACGGCAATGGGTGGAACATGGCTAGAGTCAGAAGCCTGGCCCCAGCTGCTGCTGGGAGACCCCAGACAGCACCCCGTCTCCTTTGCAGCTTC
Downstream sequence
TCATTTGGAGGTTTAAATGACTTCATTAACTATTCATTAACACATAGAAAAATCAGCCTTTCAGAAAAACACAAGCCTTTCACAAGATCTATGCCATGTC
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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