VISDB Viral Integration Site DataBase

VIS ID

TVIS42000354

Fusion event

EBV-MTHFD1L integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

138561

Orient

+

Integrated sequence

ACTAGCCTCTTCATGTGAGGTAAGAGATCGCTAAAAATGGGATCAGGGTATGTAAACCGAGTTTTGCGGGGGATGGTGAGCCAGACACGGCGGGTGGGGG| |AAGGAGCTGACACGATTGAGTAGAAAGGGCCAAAAATACACCAGCTATAAGGAATTGCTCAGGCCAAAGTTGTTCCTCAGGTGGCTTTAGGCCTAATGTA

Chromosome

chr6

Cytoband

q25.1

Reference genome

Start

End

151288487/150967351 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-887-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-218-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-564 ; hsa-mir-3622a-5p ; hsa-mir-29b-2-5p ; hsa-mir-4777-5p ; hsa-mir-526a ; hsa-mir-523-5p ; hsa-mir-522-5p ; hsa-mir-520c-5p ; hsa-mir-519c-5p ; hsa-mir-519b-5p ; hsa-mir-519a-5p ; hsa-mir-518f-5p ; hsa-mir-518e-5p ; hsa-mir-518d-5p ; hsa-mir-92a-1-5p ; hsa-mir-138-5p ; hsa-mir-6131 ; hsa-mir-133a-5p ; hsa-mir-6509-3p ; hsa-mir-1273g-3p ; hsa-mir-181a-2-3p ; hsa-mir-508-5p ; hsa-mir-3145-5p ; hsa-mir-4760-3p

Nearest miRNA

hsa-mir-10398/Upstream/10283468; hsa-mir-1202/Downstream/135324;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/100375, chr6-CpG: 25/Downstream/123516

Upstream sequence

gacagcaccttcatattggacttctcagcctccagaactgttgtttataatataaatttctgttgtttataagccatccagactatagtattttattata

Downstream sequence

CCAGGCCTGCTCGCTGCTCCTCCTCCGCTTTGCTGGCTTCTCTGATGACCCCTCACCTTTTTTGCCCCGTTCTCCTCCAGAATTAGCCAGGtgatgactc