Basic Information
VIS ID
TVIS42000358
Fusion event
EBV-GLMN integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
100014
Orient
+
Integrated sequence
ATGCGTGAACTGCCAGCGTCCTGAGGCTGCTGCTTTCCTCGGATGCCAAAGAAGACGTTGAGATGCGTGTAGCCCAGAAGCGTGTAGTTCTCGGTGGTGG| |AGGCGTAGTCCAGGAGGCCGTGAAGGAGAGGCTCGTCTGAGGTGAACTCTATGTTGTCGCGAATCAGCATGTTGTTGGTAAATGTGCAGAAGGGGAGGTC
Host Sequence
Chromosome
chr1
Cytoband
p22.1
Reference genome
GRCh37/hg19
Start
92882343/92416786 (Hg38)
End
92882343/92416786 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
GLMN
miRNAs that regulate target gene
hsa-mir-151a-3p ; hsa-mir-196a-5p ; hsa-mir-98-5p ; hsa-let-7d-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-101-1/Upstream/6059099; hsa-mir-11399/Downstream/1430046;
Nearest TSS
ENST00000473358/Upstream/83544; ENST00000646852/Downstream/67168;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/117417, chr1-CpG: 494/Downstream/63523
Upstream sequence
gataccctgttttccaggatgtgattattacacactgcatgcctgtatcaaaacatcttatataccccatcaatatatacacctactgtgtactcagaaa
Downstream sequence
aattaaaGTCTTCACAGTCACaaaaaaataaaaaagtaattttttaaaaGTTTCTATAGCAGTAGTTGGTGCTAGTGTCAGCTGAAGAAGAGCTTCTAAT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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