Basic Information
VIS ID
TVIS42000380
Fusion event
EBV-ZMYM4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
43141
Orient
+
Integrated sequence
AAGATACTAAAGAAATAACTGAGGTGAGTGTGGGAAGATGGGAATACTATGTGTTATGTTAACGGGTGAGAGCCTATACTGCAGCCCAGACTCGGGGGGA| |GGAGGAAATGGTAAGAGTTATACTCTACTTATCTTTTTTGACACTACATTTAACTGTTATGTAACAATGTTTGCTTATTTTCATGTTCAATAAACGCTAT
Host Sequence
Chromosome
chr1
Cytoband
p34.3
Reference genome
GRCh37/hg19
Start
35851517/35385916 (Hg38)
End
35851517/35385916 (Hg38)
Orient
+
Location type
Intronic
Target gene
ZMYM4
miRNAs that regulate target gene
hsa-mir-3149 ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-365b-5p ; hsa-mir-365a-5p ; hsa-mir-8052 ; hsa-mir-3199 ; hsa-mir-6789-3p ; hsa-mir-4707-3p ; hsa-mir-4258 ; hsa-mir-4438 ; hsa-mir-34a-5p ; hsa-mir-34c-5p ; hsa-mir-449a ; hsa-mir-449b-5p ; hsa-mir-4698 ; hsa-mir-4705 ; hsa-mir-548au-3p ; hsa-mir-551b-5p ; hsa-mir-7150 ; hsa-mir-8063
Nearest miRNA
hsa-mir-12136/Upstream/716222; hsa-mir-101-1/Downstream/1775647;
Nearest TSS
ENST00000473358/Upstream/19839; ENST00000470175/Downstream/6764;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/116662, chr1-CpG: 95/Downstream/171163
Upstream sequence
tgcatttttgtcaaatttcttgtagggccaagcgcagtgtggctcacacctgttatcccaatgctttgggaagccgaggcaggaggatcacttgaggcca
Downstream sequence
ggagtttgagaccagcctgggcaacatagacaccctgtctctaccaaaaacataaaaataaaaaattagtcaggcatcatggcgtgtgcctgaaatccta
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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