VISDB Viral Integration Site DataBase

VIS ID

TVIS42000383

Fusion event

EBV-PRKAA2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

71208

Orient

+

Integrated sequence

CACTTTCTGCCAGGCTCCAATCTCTGGATGGGCGGCCACCGCCAGCATCGACTGTAGGAACGGGTCTTGGATGGGCTCTAGGGTCAGAGAGGCCAGGGGG| |CTGGGCAAGGTGACAAATGTAATCTTGGAGACAGGCTTAACCAGACTCATGTCAAACCACGGTTTGTTCGGCAGGGGCCTCTGGCTGCGTTCTTGCCTCG

Chromosome

chr1

Cytoband

p32.2

Reference genome

Start

End

57124273/56658600 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-mir-182-5p ; hsa-let-7b-5p ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-510-3p ; hsa-mir-578 ; hsa-mir-526b-5p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-6853-3p ; hsa-mir-5696 ; hsa-mir-1206 ; hsa-mir-4635 ; hsa-mir-26b-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-7844-5p ; hsa-mir-302c-5p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-4729 ; hsa-mir-4719 ; hsa-mir-382-3p ; hsa-mir-500a-5p ; hsa-mir-200a-3p ; hsa-mir-141-3p ; hsa-mir-3658 ; hsa-mir-3678-3p ; hsa-mir-1273h-3p ; hsa-mir-7154-5p ; hsa-mir-3653-3p ; hsa-mir-4771 ; hsa-mir-3166 ; hsa-mir-494-3p ; hsa-mir-8060 ; hsa-mir-4761-5p ; hsa-mir-495-5p ; hsa-mir-27a-3p

Nearest miRNA

hsa-mir-12136/Upstream/1432877; hsa-mir-101-1/Downstream/3074627;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/13036, chr1-CpG: 222/Downstream/763691

Nearest cancer related gene

PRKAA2(TSG, No orient, 0)

Upstream sequence

TCCCTCCGTGTCCTCACTTTAGGCACGAGCCCCAGGTCTCTGCAACACTGTCCAGCGCTCAGCTTCTGAGACTCCAAACTGTCCTCATTCATCCTGCACC

Downstream sequence

CAGGCAGGCAGGTCCACCCCCAGCTCTTCTCATTATCCTACAGCTTATCCTGGTCAAGAGCTGCCCACCCCACCCCAACCCTGCATGAAGCCTTCTCGCC