Basic Information
VIS ID
TVIS42000384
Fusion event
EBV-PGM1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
147775
Orient
+
Integrated sequence
CTCGAGTTAGGACTTAATCGCTCCTGTGCCGCTGGATGAGGGAGCGCCAATTTGTACATCCTAGCTCTGGCCATAGAGTTAGCCCACCCTTGTGTCTCCC| |TTTGGCCTTTGCGGTGCCAATTTCCGGTGGTTTCCCTTTTCCGCCCGTTTATCCAATAGCATGTAAGAGAGGTTGCCTAGATTTGGCAACTTTGAGGGAA
Host Sequence
Chromosome
chr1
Cytoband
p31.3
Reference genome
GRCh37/hg19
Start
64058667/63592996 (Hg38)
End
64058667/63592996 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1L
Target gene
PGM1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-30a-5p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-12132/Upstream/266012; hsa-mir-101-1/Downstream/986851;
Nearest TSS
ENST00000473358/Upstream/37921; ENST00000473117/Downstream/280;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/224846, chr1-CpG: 99/Downstream/270
Upstream sequence
ggttcgtccatgttggagcatgtgttagcctttcctgccctttaaaggctgaattcgttatgtgcacaccacattttgttgatttgttcatccatccatg
Downstream sequence
ggtgcatgggttgtttcagcctttgggtattttgaataatgccatgaacataggtgtaaaatCTGAGAGCCAGACGTCTTGAAAGAGTTTTGTTTTTTTT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
Curate