Basic Information
VIS ID
TVIS42000386
Fusion event
EBV-LMO4 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
4725
Orient
+
Integrated sequence
AGGTGCAGCACGGCCCAGAGACGGTGTTGCGCCAGTCGCTGCGCCTGCTGCTGGGAACCTGGTCATCCTTTGCCAGCGAGCAGTACGAGTGCCTGCGACC| |AGATCGGATTAACCGGTCCATGCACGTGTCCGACTACGGCTATAACGAAGCACTGGCAGTCTCCCCGTTGACAGGAAAGAATCTCAGCCCACGCCGGTTG
Host Sequence
Chromosome
chr1
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
87812299/87346616 (Hg38)
End
87812299/87346616 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1D
Target gene
LMO4
Nearest miRNA
hsa-mir-101-1/Upstream/988929; hsa-mir-11399/Downstream/6500216;
Nearest TSS
ENST00000473358/Upstream/14835; ENST00000436111/Downstream/25039;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/11067, chr1-CpG: 63/Downstream/1115984
Nearest cancer related gene
LMO4(OG, No orient, 0)
Upstream sequence
GGTGGCGAGAGATGAGGCTTCTGGCTCTGTCCCTAGCCTAGGGAGGCACCCCCGGGCCTCTGTTTTCTCACCTGAGAGAAACTGCAGGCACCCACGCAGT
Downstream sequence
TCTAAATCGTGCCATAGCCCTGGCTCTGGTGGGATCTTAGTGGGGGATGCCAGATGGGAAAGAGGCTGGGTTCcaataatctgttgctagtgacaagcca
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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