VISDB Viral Integration Site DataBase

VIS ID

TVIS42000397

Fusion event

EBV-RASAL2 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

104509

Orient

+

Integrated sequence

ACCAAGCATTTCCAGTGCCAGACCGTCCTCCAGACCTTGAGACGCAAGTGCCTCGGGAGTGACACGGTCTCAAAAATAATTCCCTAGAATAAACTGAGAA| |CAGTCATCAGTAAATCTGTCTCTCGCGTGATTTCCATAGGAATGGTGTAGCCGGGGTGGAGGGCCGATATCACATCAAGCAGAAAGGCCATAATCTCTCG

Chromosome

chr1

Cytoband

q25.2

Reference genome

Start

End

178353609/178384474 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-26b-5p ; hsa-mir-15a-3p ; hsa-mir-125b-5p ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-203a-3p ; hsa-mir-6867-5p ; hsa-mir-511-3p ; hsa-mir-5583-3p ; hsa-mir-129-5p ; hsa-mir-4639-5p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-136-5p

Nearest miRNA

hsa-mir-101-1/Upstream/1355029; hsa-mir-1182/Downstream/293275;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/289763, chr1-CpG: 49/Downstream/102190

Nearest cancer related gene

RASAL2(TSG, No orient, 0)

Upstream sequence

GTCAAGTGTGTGGTGCAGCAGGAAACATTTGGAGTCGACTCCTTTACGGAACTCAAATGCCCTCACATTTAGGGAGAAATAGAAAGAATTACGACTCATG

Downstream sequence

AAATCGAGCTGGGGCTGGCACTTCTGACCCTCCCAACAGGTTTCCAGAAAGCTATTTACACACGATGCATTCGCCAAACCACTGGAAATCATTCTACCCT