Basic Information
VIS ID
TVIS42000400
Fusion event
EBV-PPP2R5A integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
146877
Orient
+
Integrated sequence
TTCCTAGATTGTACAGATGAACTAGAACTGTCACAATCTATGGGGTCGTAGACAGTGTGCTTACCAGACTTCCATGGAAGATGTGAATTTGCTGCTAGCT| |ATATGGGTGGTGCTATGGGCTCCCTAGGGACTCATGTAGTGGGGCTTTGTGATAGCTAATGAATGTGGCAGCTGTTGTTTGTACTGGACCCTGAATTGGA
Host Sequence
Chromosome
chr1
Cytoband
q32.3
Reference genome
GRCh37/hg19
Start
212531062/212357720 (Hg38)
End
212531062/212357720 (Hg38)
Orient
+
Location type
Intronic
Target gene
PPP2R5A
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-590-3p ; hsa-mir-335-5p ; hsa-mir-484
Nearest miRNA
hsa-mir-101-1/Upstream/280035; hsa-mir-1182/Downstream/7760133;
Nearest TSS
ENST00000473358/Upstream/26007; ENST00000472389/Downstream/19986;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/71368, chr1-CpG: 77/Downstream/56529
Upstream sequence
agggactcctcccaaactcattctatgaagccagcatcaccctgatactaaaacctagcaaagacacaaataaaaaagaaaactacaagccaatatcatt
Downstream sequence
gatgaacatatacacataaaatcttcagcaaaatactagaaaaccaaatctaacagcatatctaaaagctcattcaccatgatcaggtaggcttcactcc
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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