VISDB Viral Integration Site DataBase

VIS ID

TVIS42000401

Fusion event

EBV-NSL1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

128925

Orient

+

Integrated sequence

TTTTGGACTTCCTGGGAGGTGATGTAGGTTGTAGTTTCCAGGCCTTCCTTTTCATCATAACTGAGCAGGGCAAAGCCACAAAAAATGCAGGATTTCTGCG| |TCCTGGTAAAATTCTGGATCTTTGGAATCTGGCGGGGCTCCCCAGCCACAGCACCCTGCGAACATTTATTCATTATAACGGGGGAGAGAAAGAGAGAGCT

Chromosome

chr1

Cytoband

q32.3

Reference genome

Start

End

212947451/212774109 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-421 ; hsa-mir-26b-5p ; hsa-mir-146a-5p ; hsa-mir-146b-5p ; hsa-mir-181b-2-3p ; hsa-mir-181b-3p ; hsa-mir-3129-3p ; hsa-mir-410-3p ; hsa-mir-4420 ; hsa-mir-4434 ; hsa-mir-4516 ; hsa-mir-4531 ; hsa-mir-4735-5p ; hsa-mir-5583-5p ; hsa-mir-5703 ; hsa-mir-653-3p ; hsa-mir-7153-5p

Nearest miRNA

hsa-mir-101-1/Upstream/696424; hsa-mir-1182/Downstream/7343744;

Nearest TSS

Nearest CpG islands

None/Target, chr1-CpG: 111/Upstream/73403, chr1-CpG: 45/Downstream/17415

Upstream sequence

tgcctataatcccagaacttttggaggccaagacaggcggatcatctgaggtcaggagttcaagaccagcccagccaacatggtgaaactctgtctctac

Downstream sequence

taaaagtacaaaaaaaaaaaaaaaattagctgggcatggtgcaggcgcctgtaatctcagcttcttgggaggctgaggcaggagaatcacttgaacccgg