Basic Information
VIS ID
TVIS42000404
Fusion event
EBV-RYR2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
163314
Orient
+
Integrated sequence
GTGGGTCATGTAGAAACTGTTAAAGAGACTCTCCTTGCCCTGACCGGTTGACTTCGAGACCCCCGAGACGTAGAGGACGGAATTGGTGGCAAAGATCTGC| |GTGGACACGTGGGGGGCCAGGCTGGCATTATATCGGTGTAACGCAGCCACACGGGCCTCTGGACCCTCACAGTCGGCAAACAGGGGCCACGAGTCGTAGT
Host Sequence
Chromosome
chr1
Cytoband
q43
Reference genome
GRCh37/hg19
Start
237968083/237804783 (Hg38)
End
237968083/237804783 (Hg38)
Orient
-
Location type
Intronic
Target gene
RYR2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-25-3p ; hsa-mir-17-5p ; hsa-let-7c-5p
Nearest miRNA
hsa-mir-101-1/Upstream/333592; hsa-mir-3123/Downstream/3327489;
Nearest TSS
ENST00000473358/Upstream/4754; ENST00000462585/Downstream/25249;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/20635, chr1-CpG: 91/Downstream/1582172
Upstream sequence
ctggaggtatcacgctgcctgacttcaaactatactacaaggctgcagtaaccaaaacagcatggtgctggtaccaaaacagagatatagaccaatggaa
Downstream sequence
aagaacagagccctcaaaaataataccacacatctacaactatctgatctttgacaaacctgagaaaaacaagacatggggaaaggattccctatttaat
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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