VISDB Viral Integration Site DataBase

VIS ID

TVIS42000420

Fusion event

EBV-ZMIZ1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

6790

Orient

+

Integrated sequence

CCCGGGTACAAGTCCCGGGTGGTGAGGACGGTGTCTGTGGTTGTCTTCCCAGACTCTGCTTTCTGCCGTCTTCGGTCAAGTACCAGCTGGTGGTCCGCAT| |GTTTTGATCCAAACTTTTGTTTTAGGATTTATGCATCCATTATCCCGCAGTTCCACCTAAACGGGGCTTAACGTTGCATCCCAGAAGATGCACGCTTAAC

Chromosome

chr10

Cytoband

q22.3

Reference genome

Start

End

80971810/79212053 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-96-5p ; hsa-mir-93-5p ; hsa-mir-1180-3p ; hsa-mir-1301-3p ; hsa-mir-1185-1-3p ; hsa-mir-1185-2-3p ; hsa-mir-4652-3p ; hsa-mir-4743-3p ; hsa-let-7g-3p ; hsa-let-7a-2-3p ; hsa-let-7c-3p ; hsa-mir-29b-2-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-4769-5p ; hsa-mir-4654 ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-4648 ; hsa-mir-8069 ; hsa-mir-134-3p ; hsa-mir-7114-5p ; hsa-mir-493-5p ; hsa-mir-1249-5p ; hsa-mir-331-3p ; hsa-mir-4313 ; hsa-mir-6515-5p ; hsa-mir-6715a-3p ; hsa-mir-6715b-3p ; hsa-mir-6757-5p ; hsa-mir-6797-5p ; hsa-mir-6798-5p ; hsa-mir-6846-3p ; hsa-mir-6859-3p ; hsa-mir-874-5p ; hsa-mir-1264 ; hsa-mir-3657 ; hsa-mir-4433a-5p ; hsa-mir-4433b-5p ; hsa-mir-4455 ; hsa-mir-4795-5p ; hsa-mir-609 ; hsa-mir-662 ; hsa-mir-6748-5p ; hsa-mir-6772-5p

Nearest miRNA

hsa-mir-1265/Upstream/3659500; hsa-mir-107/Downstream/7052641;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/141595, chr10-CpG: 148/Downstream/30225

Upstream sequence

TCTCTACCTTACCATCTGCATTTGTTTTTTCTTTTTGATTGGGTGGCATTCACCTGGGCTTTCCTTCACTTCCTGACGATTCAAGATGGCAATTCTCATC

Downstream sequence

TCTGGTCAGGCTGAGCTTCTCTCAGCAGCTCCTGACATTTCCTCCAGCTTGTCTCACCTTCTCAGTTGTCTCCCATTCCCACCAGCACATCCTTTGACCT