Basic Information
VIS ID
TVIS42000426
Fusion event
EBV-TLL2 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
103479
Orient
-
Integrated sequence
TGGGAAAGCGAGCTGTTTAACACCTTCAAGTTAACACCCGTGGTTGATAATCAGGGGCAGCGTCTCTACGTCAGATACTCGTCAGACACGATCTCTATAT| |TATTGGGCCCCTTCACCTATCTGGTGGCAGAGCTTTCACCGGTGGAACTCGTGACAGATGTCTACGCCACCCTAGGCATCGTGGAGATCATCGACGAGCT
Host Sequence
Chromosome
chr10
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
98137938/96378181 (Hg38)
End
98137938/96378181 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
TLL2
miRNAs that regulate target gene
hsa-mir-944 ; hsa-mir-4803 ; hsa-mir-548c-3p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-2277-3p
Nearest miRNA
hsa-mir-107/Upstream/313782; hsa-mir-1287/Downstream/450488;
Nearest TSS
ENST00000439456/Upstream/2820; ENST00000469510/Downstream/135730;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/247526, chr10-CpG: 20/Downstream/6361
Upstream sequence
AATTGCACATCAAGAAGGAAACAAGGCATAAAGAGGACCAATTTGGGGAATTTCTCTCCCCACTGGAATGCACGTGATACTCATTAAGGGTGTAGAAATT
Downstream sequence
GTGTCATTCCATCCAGAGGGTTAAATTACCTACAGAGCTTTCATTTATTCAGGTTTTATTTAAGTAGCCTTTGGGGAAGACTCCTTTTTCCCTCTTTGGA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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