Basic Information
VIS ID
TVIS42000427
Fusion event
EBV-ARHGAP19-SLIT1 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
161486
Orient
+
Integrated sequence
CTAGGGTGGGGGTGGCAAAGACAAACTTCTTCCGCATGGAAGAGCCCCCGGCCTGCTTGCGCAGCCCAGCCCCGGGGGCCTGCAGCAGGTTCCTGTCCAC| |GCCCCGGCCCATAAAGTATCCCAGGTTCCCGGCCTGGAATATCTGGTTGTTGCCGTTGACCCCCGTGTACTTGTTGATGGTCACTGGCAGCGTGACAACC
Host Sequence
Chromosome
chr10
Cytoband
q24.1
Reference genome
GRCh37/hg19
Start
98977496/97217739 (Hg38)
End
98977496/97217739 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
ARHGAP19-SLIT1
miRNAs that regulate target gene
hsa-mir-211-3p ; hsa-mir-214-3p ; hsa-mir-3619-5p ; hsa-mir-365a-5p ; hsa-mir-365b-5p ; hsa-mir-4530 ; hsa-mir-617 ; hsa-mir-6510-5p ; hsa-mir-6858-3p ; hsa-mir-761
Nearest miRNA
hsa-mir-107/Upstream/388975; hsa-mir-1287/Downstream/658074;
Nearest TSS
ENST00000439456/Upstream/31819; ENST00000490980/Downstream/38776;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/21211, chr10-CpG: 48/Downstream/74438
Upstream sequence
AATCTGATTGTTTCACCAAGCTGAAAAACAAGAAACGAAAAGTAACAACAACAAGACAAACTTAGGCCATGTATATCTGCCCTGAAAAACACAAATCAAT
Downstream sequence
ATATATAATCTTGAAAAACAGCGACCATAAGAAATTAACAACTGTCTTCTCTCAGTATTGGTAGAGTATTGGGTTGTGAACTCATGAAGAAAGAATTAAA
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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