VISDB Viral Integration Site DataBase

VIS ID

TVIS42000436

Fusion event

EBV-SOX6 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

137833

Orient

+

Integrated sequence

GAGACTAATGTGGTGGGGGCTATGGTAGTGGCTGGGATAACAGTAAGATGCATACGCTGAGTGAGGGTCCGGTTGGCATGGTATTGGTCGTCTTCTTCCC| |CTGCAGAGTAATTGCAGTGGACCCCGGAGGCCACACTGCAATTTCTCAGTGTCACATTGCACGTGTAGTAACCTGCATGCGCAAGGGTCACATTGGGGAT

Chromosome

chr11

Cytoband

p15.2

Reference genome

Start

End

16236457/16214911 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA11C ; FRA11I

Target gene

miRNAs that regulate target gene

hsa-mir-1-3p ; hsa-mir-499a-5p ; hsa-mir-155-5p ; hsa-mir-16-5p ; hsa-mir-208a-3p ; hsa-mir-3148 ; hsa-mir-4668-5p ; hsa-mir-562 ; hsa-mir-651-3p ; hsa-mir-548n ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-1269a ; hsa-mir-132-3p ; hsa-mir-202-3p ; hsa-mir-1273h-5p ; hsa-mir-129-5p ; hsa-mir-30b-3p ; hsa-mir-30c-1-3p ; hsa-mir-30c-2-3p ; hsa-mir-3122 ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-3913-5p ; hsa-mir-450a-1-3p ; hsa-mir-6513-5p ; hsa-mir-6731-5p ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6788-5p ; hsa-mir-6878-5p ; hsa-mir-8085 ; hsa-mir-887-5p

Nearest miRNA

hsa-mir-210/Upstream/245290; hsa-let-7a-2/Downstream/2172876;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/273234, chr11-CpG: 101/Downstream/389595

Upstream sequence

ggcaaaagtgggaagaacttcatcttgtggtttgaacctcagctcaactgcaatataatagaacaccaggtagccctctaatgtttttgactctagtcct

Downstream sequence

tgacttctggacagcacatctgtatctcagggcctgaggaatctcactgccctgatgggaagcacacaggccttgctggctttgctaccttctgattgta