VISDB Viral Integration Site DataBase

VIS ID

TVIS42000446

Fusion event

EBV-CADM1 integration

Validated

No

Detection method

WGS

Data source

Curated

Sample type

Disease

B-cell lymphoma (BL)

Quality evaluation

Normal

Reported year

2005

PubMed ID

Virus name

EBV

Reference genome

Start

120048

Orient

+

Integrated sequence

TCCCTCCCGAGGTCGTGGGGCCGGAGCCTTATAAAAGACTTCCACCCTCTCCCCGCTGGCCAAGACACGCCGCTCGTGGACCACGCCATCTTCCTCCCGG| |CTGATTGTGTGGCTGACGGTGCCGTGTTCCACCGCCACTTGTTCATCGACCATGGTACCCCCTTTATCTTAACCAGCAAGTGGCCGTCAGGGTCTCTTGA

Chromosome

chr11

Cytoband

q23.3

Reference genome

Start

End

115353564/115482845 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

FRA11G ; FRA11B

Target gene

miRNAs that regulate target gene

hsa-mir-15a-5p ; hsa-mir-192-5p ; hsa-mir-16-5p ; hsa-mir-26b-5p ; hsa-mir-877-3p ; hsa-mir-484 ; hsa-mir-182-5p ; hsa-let-7a-2-3p ; hsa-let-7g-3p ; hsa-mir-214-3p ; hsa-mir-486-5p ; hsa-mir-4644 ; hsa-mir-4306 ; hsa-mir-185-5p ; hsa-mir-4479 ; hsa-mir-6770-5p ; hsa-mir-361-3p ; hsa-mir-4428 ; hsa-mir-6885-3p ; hsa-mir-1273e ; hsa-mir-6892-5p ; hsa-mir-4327 ; hsa-mir-6512-5p ; hsa-mir-4475 ; hsa-mir-4484 ; hsa-mir-6768-3p ; hsa-mir-548an ; hsa-mir-3692-3p ; hsa-mir-4703-3p ; hsa-mir-140-3p ; hsa-mir-7852-3p ; hsa-mir-144-3p ; hsa-mir-101-3p ; hsa-mir-6732-3p ; hsa-mir-652-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-7161-3p ; hsa-mir-126-3p ; hsa-mir-21-5p ; hsa-mir-302c-5p ; hsa-mir-552-5p

Nearest miRNA

hsa-mir-10392/Upstream/2032757; hsa-let-7a-2/Downstream/3161155;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/328621, chr11-CpG: 178/Downstream/20011

Nearest cancer related gene

CADM1(TSG, No orient, 0)

Upstream sequence

gtggaacacctgaggtcaggagttcaagaccagcctggccaacatggcaaaaccctgtctctattaaaaacacaaaaattagcctggcatggtggcaggc

Downstream sequence

gcctataatcccaactactcaggaggctgaggcaggagaatcgcttgaacccaagagagtgaaggttgcagtgagctgagatcatgccacttcactccag