Basic Information
VIS ID
TVIS42000451
Fusion event
EBV-FGF6 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
44844
Orient
+
Integrated sequence
TCCACGAGGATTGTTTTGCCCACTCTGGCCACTTGTGTGGATTTAAATATGTACACAAGCGTAATTAACGAGTCACAGACCCCCTGTTCCAGATTCTGAC| |CGGCTGCAAGCGCTGCCTTAAAGGCCTGGAAGCTGGGTGGGTAAATCTGACCAAACAGCACGCTCGGATTCGTGATGCTGTGGTTGATGGCACACAGGGG
Host Sequence
Chromosome
chr12
Cytoband
p13.32
Reference genome
GRCh37/hg19
Start
4552589/4443423 (Hg38)
End
4552589/4443423 (Hg38)
Orient
+
Location type
Intronic
Target gene
FGF6
Nearest miRNA
hsa-mir-3649/Upstream/2783043; hsa-let-7i/Downstream/2520276;
Nearest TSS
ENST00000382841/Upstream/14708; ENST00000538817/Downstream/796;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/72616, chr12-CpG: 17/Downstream/1816
Nearest cancer related gene
FGF6(OG, No orient, 0)
Upstream sequence
GTAGCAAAATGTAGGTGCGGGGGGGTTAAAATAATTTTTCCATGAATTTAGAAGAGTCCTAAGCTTCAAGAAAATATCTTATGTGCTTTATTTAAAATAA
Downstream sequence
AACAGCCTCCAACCTCACCAGAGACAGGAAATGTCATATTCCAGGGAGAGTACCCCACCCCCACCACCACTCACCTTGGAATTTCCGGGAGCTGAGCAGT
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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