Basic Information
VIS ID
TVIS42000455
Fusion event
EBV-MRPS28 integration
Validated
No
Detection method
WGS
Data source
Curated
Sample type
Cell line
Disease
B-cell lymphoma (BL)
Quality evaluation
Normal
Reported year
2005
PubMed ID
15681063
Virus Sequence
Virus name
EBV
Reference genome
NC007605
Start
130164
Orient
+
Integrated sequence
ATCACCAGGGAATAGTCCCCGCTTTGGGCACTGGTTAAGGATGGGTAACTAAAAGGCCCCCTCAGATCCGGCAGGTCCTTCGTCTTGCCAAAGACCAGGC| |TCAACACATGCTCATCTCCCTTCTCGGTCACTCGCTTGTAGGTGCCCATCAGAAATTTAGAAGTCATGGCCCCCGTGTACTGAAACTTGTCCCCGTTGAT
Host Sequence
Chromosome
chr12
Cytoband
p11.22
Reference genome
GRCh37/hg19
Start
27909403/27756470 (Hg38)
End
27909403/27756470 (Hg38)
Orient
+
Location type
Intronic
Target gene
MRPS28
miRNAs that regulate target gene
hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1244-3/Upstream/1882391; hsa-let-7i/Downstream/14567230;
Nearest TSS
ENST00000382841/Upstream/45583; ENST00000540301/Downstream/14806;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/45322, chr12-CpG: 124/Downstream/23348
Upstream sequence
tggatcacctgaggtcaggatgttcaagaccagcctgaccaacatggtgaaaccccatctctattaaaaatacaaaaaattagacgggggtgatggcgag
Downstream sequence
cgcctgtaatcccagctactctggaggctgaggcaggagaatcgcttgaacctgggaggcggaggttgcagtgagctaagattgcaccattgcactccag
Reference
Takakuwa, T., et al. Identification of Epstein-Barr virus integrated sites in lymphoblastoid cell line (IB4). Virus Res,2005, 108(1-2): 133-138.
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